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Measuring proteins in H(2)O with 2D-IR spectroscopy

The amide I infrared band of proteins is highly sensitive to secondary structure, but studies under physiological conditions are prevented by strong, overlapping water absorptions, motivating the widespread use of deuterated solutions. H/D exchange raises fundamental questions regarding the impact o...

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Detalles Bibliográficos
Autores principales:	Hume, Samantha, Hithell, Gordon, Greetham, Gregory M., Donaldson, Paul M., Towrie, Michael, Parker, Anthony W., Baker, Matthew J., Hunt, Neil T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611063/ https://www.ncbi.nlm.nih.gov/pubmed/31341597 http://dx.doi.org/10.1039/c9sc01590f

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