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mTOR as a central regulator of lifespan and aging
The mammalian/mechanistic target of rapamycin (mTOR) is a key component of cellular metabolism that integrates nutrient sensing with cellular processes that fuel cell growth and proliferation. Although the involvement of the mTOR pathway in regulating life span and aging has been studied extensively...
Autores principales: | Papadopoli, David, Boulay, Karine, Kazak, Lawrence, Pollak, Michael, Mallette, Frédérick A., Topisirovic, Ivan, Hulea, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611156/ https://www.ncbi.nlm.nih.gov/pubmed/31316753 http://dx.doi.org/10.12688/f1000research.17196.1 |
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