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Could AGE/RAGE-Related Oxidative Homeostasis Dysregulation Enhance Susceptibility to Pathogenesis of Cardio-Metabolic Complications in Childhood Obesity?

Background: Advanced glycation end-products (AGEs) and their cell receptor (RAGE) are involved in the pathophysiology of cardio-metabolic diseases. Interaction of AGEs with RAGE results in increased generation of oxygen radicals and pro-inflammatory cytokines. Circulating soluble RAGE (sRAGE) intera...

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Detalles Bibliográficos
Autores principales:	Corica, Domenico, Aversa, Tommaso, Ruggeri, Rosaria Maddalena, Cristani, Mariateresa, Alibrandi, Angela, Pepe, Giorgia, De Luca, Filippo, Wasniewska, Malgorzata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611173/ https://www.ncbi.nlm.nih.gov/pubmed/31316471 http://dx.doi.org/10.3389/fendo.2019.00426

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