Key Features Relevant to Select Antigens and TCR From the MHC-Mismatched Repertoire to Treat Cancer

Adoptive transfer of T cells transgenic for tumor-reactive T-cell receptors (TCR) is an attractive immunotherapeutic approach. However, clinical translation is so far limited due to challenges in the identification of suitable target antigens as well as TCRs that are concurrent safe and efficient. D...

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Detalles Bibliográficos
Autores principales: Audehm, Stefan, Glaser, Manuel, Pecoraro, Matteo, Bräunlein, Eva, Mall, Sabine, Klar, Richard, Effenberger, Manuel, Albers, Julian, Bianchi, Henrique de Oliveira, Peper, Janet, Yusufi, Nahid, Busch, Dirk H., Stevanović, Stefan, Mann, Matthias, Antes, Iris, Krackhardt, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611213/
https://www.ncbi.nlm.nih.gov/pubmed/31316521
http://dx.doi.org/10.3389/fimmu.2019.01485

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