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Clinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease

Vogt-Koyanagi-Harada (VKH) disease is a systemic disorder causing bilateral panuveitis. Histopathological documentation along with molecular diagnostic evidence in VKH eye is a rarity. We present a 46-year-old woman with VKH with several ocular complications and subsequently enucleation of the right...

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Autores principales: Das, Dipankar, Boddepalli, Anusha, Biswas, Jyotirmay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611308/
https://www.ncbi.nlm.nih.gov/pubmed/31238472
http://dx.doi.org/10.4103/ijo.IJO_1800_18
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author Das, Dipankar
Boddepalli, Anusha
Biswas, Jyotirmay
author_facet Das, Dipankar
Boddepalli, Anusha
Biswas, Jyotirmay
author_sort Das, Dipankar
collection PubMed
description Vogt-Koyanagi-Harada (VKH) disease is a systemic disorder causing bilateral panuveitis. Histopathological documentation along with molecular diagnostic evidence in VKH eye is a rarity. We present a 46-year-old woman with VKH with several ocular complications and subsequently enucleation of the right eye was done because of painful blind eye. Patient had clinical complications of VKH and some of the complications were observed in histopathology. Pathology of the case showed nongranulomatous uveitis, indicating the disease in chronic recurrent stage. Immunohistochemistry showed predominant T-cell involvement in this case. The case showed clinicopathological and immunohistochemistry correlation in a case of VKH disease.
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spelling pubmed-66113082019-07-22 Clinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease Das, Dipankar Boddepalli, Anusha Biswas, Jyotirmay Indian J Ophthalmol Case Reports Vogt-Koyanagi-Harada (VKH) disease is a systemic disorder causing bilateral panuveitis. Histopathological documentation along with molecular diagnostic evidence in VKH eye is a rarity. We present a 46-year-old woman with VKH with several ocular complications and subsequently enucleation of the right eye was done because of painful blind eye. Patient had clinical complications of VKH and some of the complications were observed in histopathology. Pathology of the case showed nongranulomatous uveitis, indicating the disease in chronic recurrent stage. Immunohistochemistry showed predominant T-cell involvement in this case. The case showed clinicopathological and immunohistochemistry correlation in a case of VKH disease. Wolters Kluwer - Medknow 2019-07 /pmc/articles/PMC6611308/ /pubmed/31238472 http://dx.doi.org/10.4103/ijo.IJO_1800_18 Text en Copyright: © 2019 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Reports
Das, Dipankar
Boddepalli, Anusha
Biswas, Jyotirmay
Clinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease
title Clinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease
title_full Clinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease
title_fullStr Clinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease
title_full_unstemmed Clinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease
title_short Clinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease
title_sort clinicopathological and immunohistochemistry correlation in a case of vogt-koyanagi-harada disease
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611308/
https://www.ncbi.nlm.nih.gov/pubmed/31238472
http://dx.doi.org/10.4103/ijo.IJO_1800_18
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