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Clinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease
Vogt-Koyanagi-Harada (VKH) disease is a systemic disorder causing bilateral panuveitis. Histopathological documentation along with molecular diagnostic evidence in VKH eye is a rarity. We present a 46-year-old woman with VKH with several ocular complications and subsequently enucleation of the right...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611308/ https://www.ncbi.nlm.nih.gov/pubmed/31238472 http://dx.doi.org/10.4103/ijo.IJO_1800_18 |
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author | Das, Dipankar Boddepalli, Anusha Biswas, Jyotirmay |
author_facet | Das, Dipankar Boddepalli, Anusha Biswas, Jyotirmay |
author_sort | Das, Dipankar |
collection | PubMed |
description | Vogt-Koyanagi-Harada (VKH) disease is a systemic disorder causing bilateral panuveitis. Histopathological documentation along with molecular diagnostic evidence in VKH eye is a rarity. We present a 46-year-old woman with VKH with several ocular complications and subsequently enucleation of the right eye was done because of painful blind eye. Patient had clinical complications of VKH and some of the complications were observed in histopathology. Pathology of the case showed nongranulomatous uveitis, indicating the disease in chronic recurrent stage. Immunohistochemistry showed predominant T-cell involvement in this case. The case showed clinicopathological and immunohistochemistry correlation in a case of VKH disease. |
format | Online Article Text |
id | pubmed-6611308 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-66113082019-07-22 Clinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease Das, Dipankar Boddepalli, Anusha Biswas, Jyotirmay Indian J Ophthalmol Case Reports Vogt-Koyanagi-Harada (VKH) disease is a systemic disorder causing bilateral panuveitis. Histopathological documentation along with molecular diagnostic evidence in VKH eye is a rarity. We present a 46-year-old woman with VKH with several ocular complications and subsequently enucleation of the right eye was done because of painful blind eye. Patient had clinical complications of VKH and some of the complications were observed in histopathology. Pathology of the case showed nongranulomatous uveitis, indicating the disease in chronic recurrent stage. Immunohistochemistry showed predominant T-cell involvement in this case. The case showed clinicopathological and immunohistochemistry correlation in a case of VKH disease. Wolters Kluwer - Medknow 2019-07 /pmc/articles/PMC6611308/ /pubmed/31238472 http://dx.doi.org/10.4103/ijo.IJO_1800_18 Text en Copyright: © 2019 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Reports Das, Dipankar Boddepalli, Anusha Biswas, Jyotirmay Clinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease |
title | Clinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease |
title_full | Clinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease |
title_fullStr | Clinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease |
title_full_unstemmed | Clinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease |
title_short | Clinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease |
title_sort | clinicopathological and immunohistochemistry correlation in a case of vogt-koyanagi-harada disease |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611308/ https://www.ncbi.nlm.nih.gov/pubmed/31238472 http://dx.doi.org/10.4103/ijo.IJO_1800_18 |
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