Site-Specific Reprogramming of Macrophage Responsiveness to Bacterial Lipopolysaccharide in Obesity

The mechanisms by which obesity may alter immune responses to pathogens are poorly understood. The present study assessed whether the intrinsic responsiveness of resident macrophages to bacterial lipopolysaccharide (LPS) is reprogrammed in high-fat diet (HFD)-induced obesity. Macrophages from adipos...

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Detalles Bibliográficos
Autores principales: Komegae, Evilin N., Fonseca, Monique T., da Silveira Cruz-Machado, Sanseray, Turato, Walter M., Filgueiras, Luciano R., Markus, Regina P., Steiner, Alexandre A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611339/
https://www.ncbi.nlm.nih.gov/pubmed/31316525
http://dx.doi.org/10.3389/fimmu.2019.01496

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