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An Exploratory Study of Consanguinity and Dental Developmental Anomalies

BACKGROUND: Consanguinity is known to alter the population structure but the available literature is almost silent on the association of dental conditions with consanguinity. AIM: The purpose was to assess the various dental developmental anomalies in 6–9 year old children born out of consanguineous...

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Autor principal: Khan, Saima Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611533/
https://www.ncbi.nlm.nih.gov/pubmed/31303740
http://dx.doi.org/10.5005/jp-journals-10005-1567
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author Khan, Saima Y
author_facet Khan, Saima Y
author_sort Khan, Saima Y
collection PubMed
description BACKGROUND: Consanguinity is known to alter the population structure but the available literature is almost silent on the association of dental conditions with consanguinity. AIM: The purpose was to assess the various dental developmental anomalies in 6–9 year old children born out of consanguineous and non-consanguineous marriages and its association with their parents. DESIGN: A cross sectional house–hold survey with a sample size of 2,000 (1,600 non-consanguineous and 400 consanguineous respondents and their parents) using systematic random sampling was planned. Six to nine-year-old children and their parents living in 1,597 households were examined and the information recorded on a pretested self prepared questionnaire. The questionnaire had questions pertaining to personal details, type of consanguineous marriages, history of trauma and examination of dental developmental anomalies. RESULTS: Multivariate logistic regression showed that non syndromic supernumerary teeth in fathers (p =.009); fusion in mothers (p = 0.002); fusion (p <0.001), nonsyndromic supernumerary teeth (p < 0.001), and microdontia (p = 0.002) in respondents were significantly associated with consanguinity. CONCLUSION: A significant association of developmental anomalies in parents with consanguineous marriages and their respondents was observed. HOW TO CITE THIS ARTICLE: Khan SY. An Exploratory Study of Consanguinity and Dental Developmental Anomalies. Int J Clin Pediatr Dent, 2018;11(6):513-518
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spelling pubmed-66115332019-07-14 An Exploratory Study of Consanguinity and Dental Developmental Anomalies Khan, Saima Y Int J Clin Pediatr Dent Research Article BACKGROUND: Consanguinity is known to alter the population structure but the available literature is almost silent on the association of dental conditions with consanguinity. AIM: The purpose was to assess the various dental developmental anomalies in 6–9 year old children born out of consanguineous and non-consanguineous marriages and its association with their parents. DESIGN: A cross sectional house–hold survey with a sample size of 2,000 (1,600 non-consanguineous and 400 consanguineous respondents and their parents) using systematic random sampling was planned. Six to nine-year-old children and their parents living in 1,597 households were examined and the information recorded on a pretested self prepared questionnaire. The questionnaire had questions pertaining to personal details, type of consanguineous marriages, history of trauma and examination of dental developmental anomalies. RESULTS: Multivariate logistic regression showed that non syndromic supernumerary teeth in fathers (p =.009); fusion in mothers (p = 0.002); fusion (p <0.001), nonsyndromic supernumerary teeth (p < 0.001), and microdontia (p = 0.002) in respondents were significantly associated with consanguinity. CONCLUSION: A significant association of developmental anomalies in parents with consanguineous marriages and their respondents was observed. HOW TO CITE THIS ARTICLE: Khan SY. An Exploratory Study of Consanguinity and Dental Developmental Anomalies. Int J Clin Pediatr Dent, 2018;11(6):513-518 Jaypee Brothers Medical Publishers 2018 /pmc/articles/PMC6611533/ /pubmed/31303740 http://dx.doi.org/10.5005/jp-journals-10005-1567 Text en Copyright © 2018; Jaypee Brothers Medical Publishers (P) Ltd. This work is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/
spellingShingle Research Article
Khan, Saima Y
An Exploratory Study of Consanguinity and Dental Developmental Anomalies
title An Exploratory Study of Consanguinity and Dental Developmental Anomalies
title_full An Exploratory Study of Consanguinity and Dental Developmental Anomalies
title_fullStr An Exploratory Study of Consanguinity and Dental Developmental Anomalies
title_full_unstemmed An Exploratory Study of Consanguinity and Dental Developmental Anomalies
title_short An Exploratory Study of Consanguinity and Dental Developmental Anomalies
title_sort exploratory study of consanguinity and dental developmental anomalies
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611533/
https://www.ncbi.nlm.nih.gov/pubmed/31303740
http://dx.doi.org/10.5005/jp-journals-10005-1567
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