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Maturation of three-dimensional, hiPSC-derived cardiomyocyte spheroids utilizing cyclic, uniaxial stretch and electrical stimulation

Functional myocardium derived from human induced pluripotent stem cells (hiPSCs) can be impactful for cardiac disease modeling, drug testing, and the repair of injured myocardium. However, when hiPSCs are differentiated into cardiomyocytes, they do not possess characteristics of mature myocytes whic...

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Detalles Bibliográficos
Autores principales:	LaBarge, Wesley, Mattappally, Saidulu, Kannappan, Ramaswamy, Fast, Vladimir G., Pretorius, Daniëlle, Berry, Joel L., Zhang, Jianyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611624/ https://www.ncbi.nlm.nih.gov/pubmed/31276558 http://dx.doi.org/10.1371/journal.pone.0219442

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