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Optimizing the alignment of thermoresponsive poly(N-isopropyl acrylamide) electrospun nanofibers for tissue engineering applications: A factorial design of experiments approach

Thermoresponsive polymers, such as poly(N-isopropyl acrylamide) (PNIPAM), have been identified and used as cell culture substrates, taking advantage of the polymer’s lower critical solution temperature (LCST) to mechanically harvest cells. This technology bypasses the use of biochemical enzymes that...

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Detalles Bibliográficos
Autores principales: Young, Rachel E., Graf, Jodi, Miserocchi, Isabella, Van Horn, Ryan M., Gordon, Melissa B., Anderson, Christopher R., Sefcik, Lauren S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611625/
https://www.ncbi.nlm.nih.gov/pubmed/31276542
http://dx.doi.org/10.1371/journal.pone.0219254