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Optimizing the alignment of thermoresponsive poly(N-isopropyl acrylamide) electrospun nanofibers for tissue engineering applications: A factorial design of experiments approach
Thermoresponsive polymers, such as poly(N-isopropyl acrylamide) (PNIPAM), have been identified and used as cell culture substrates, taking advantage of the polymer’s lower critical solution temperature (LCST) to mechanically harvest cells. This technology bypasses the use of biochemical enzymes that...
Autores principales: | Young, Rachel E., Graf, Jodi, Miserocchi, Isabella, Van Horn, Ryan M., Gordon, Melissa B., Anderson, Christopher R., Sefcik, Lauren S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611625/ https://www.ncbi.nlm.nih.gov/pubmed/31276542 http://dx.doi.org/10.1371/journal.pone.0219254 |
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