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Congenital lipodystrophy induces severe osteosclerosis
Berardinelli-Seip congenital generalized lipodystrophy is associated with increased bone mass suggesting that fat tissue regulates the skeleton. Because there is little mechanistic information regarding this issue, we generated "fat-free" (FF) mice completely lacking visible visceral, subc...
Autores principales: | Zou, Wei, Rohatgi, Nidhi, Brestoff, Jonathan R., Zhang, Yan, Scheller, Erica L., Craft, Clarissa S., Brodt, Michael D., Migotsky, Nicole, Silva, Matthew J., Harris, Charles A., Teitelbaum, Steven L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611650/ https://www.ncbi.nlm.nih.gov/pubmed/31233501 http://dx.doi.org/10.1371/journal.pgen.1008244 |
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