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Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes

Ttriple-negative breast cancer (TNBC) is an aggressive and highly metastatic breast cancer subtype. Enhanced TNBC cell motility is a prerequisite of TNBC cell dissemination. Here, we apply an imaging-based RNAi phenotypic cell migration screen using two highly motile TNBC cell lines (Hs578T and MDA-...

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Detalles Bibliográficos
Autores principales:	Koedoot, Esmee, Fokkelman, Michiel, Rogkoti, Vasiliki-Maria, Smid, Marcel, van de Sandt, Iris, de Bont, Hans, Pont, Chantal, Klip, Janna E., Wink, Steven, Timmermans, Mieke A., Wiemer, Erik A. C., Stoilov, Peter, Foekens, John A., Le Dévédec, Sylvia E., Martens, John W. M., van de Water, Bob
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611796/ https://www.ncbi.nlm.nih.gov/pubmed/31278301 http://dx.doi.org/10.1038/s41467-019-11020-3

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