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Group A Streptococcus Adsorbed Vaccine: Repeated Intramuscular Dose Toxicity Test in Minipigs
Streptococcus pyogenes infection continues to be a worldwide public health problem causing various diseases in humans and plays an important role in the pathogenesis of rheumatic fever and rheumatic heart disease. We developed a vaccine candidate to prevent S. pyogenes infections, identified as Stre...
Autores principales: | Postol, Edilberto, Sá-Rocha, Luiz C., Sampaio, Roney O., Demarchi, Lea M. M. F., Alencar, Raquel E., Abduch, Maria C. D., Kalil, Jorge, Guilherme, Luiza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611820/ https://www.ncbi.nlm.nih.gov/pubmed/31278336 http://dx.doi.org/10.1038/s41598-019-46244-2 |
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