Pre-existing H4K16ac levels in euchromatin drive DNA repair by homologous recombination in S-phase

The homologous recombination (HR) repair pathway maintains genetic integrity after DNA double-strand break (DSB) damage and is particularly crucial for maintaining fidelity of expressed genes. Histone H4 acetylation on lysine 16 (H4K16ac) is associated with transcription, but how pre-existing H4K16a...

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Detalles Bibliográficos
Autores principales: Horikoshi, Nobuo, Sharma, Dharmendra, Leonard, Fransisca, Pandita, Raj K., Charaka, Vijaya K., Hambarde, Shashank, Horikoshi, Nobuko T., Gaur Khaitan, Puja, Chakraborty, Sharmistha, Cote, Jacques, Godin, Biana, Hunt, Clayton R., Pandita, Tej K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611875/
https://www.ncbi.nlm.nih.gov/pubmed/31286070
http://dx.doi.org/10.1038/s42003-019-0498-z

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