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A practical guide for mutational signature analysis in hematological malignancies

Analysis of mutational signatures is becoming routine in cancer genomics, with implications for pathogenesis, classification, prognosis, and even treatment decisions. However, the field lacks a consensus on analysis and result interpretation. Using whole-genome sequencing of multiple myeloma (MM), c...

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Detalles Bibliográficos
Autores principales:	Maura, Francesco, Degasperi, Andrea, Nadeu, Ferran, Leongamornlert, Daniel, Davies, Helen, Moore, Luiza, Royo, Romina, Ziccheddu, Bachisio, Puente, Xose S., Avet-Loiseau, Herve, Campbell, Peter J., Nik-Zainal, Serena, Campo, Elias, Munshi, Nikhil, Bolli, Niccolò
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611883/ https://www.ncbi.nlm.nih.gov/pubmed/31278357 http://dx.doi.org/10.1038/s41467-019-11037-8

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