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Regulation of sclerostin in glucocorticoid-induced osteoporosis (GIO) in mice and humans
Glucocorticoids (GC) are used for the treatment of inflammatory diseases, including various forms of arthritis. However, their use is limited, amongst others, by adverse effects on bone. The Wnt and bone formation inhibitor sclerostin was recently implicated in the pathogenesis of GC-induced osteopo...
Autores principales: | Thiele, Sylvia, Hannemann, Anke, Winzer, Maria, Baschant, Ulrike, Weidner, Heike, Nauck, Matthias, Thakker, Rajesh V, Bornhäuser, Martin, Hofbauer, Lorenz C, Rauner, Martina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612066/ https://www.ncbi.nlm.nih.gov/pubmed/31234141 http://dx.doi.org/10.1530/EC-19-0104 |
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