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Synthesized natural peptides from amphibian skin secretions increase the efficacy of a therapeutic vaccine by recruiting more T cells to the tumour site

BACKGROUND: Therapeutic vaccines against cervical cancer remain ineffective. Previously, we demonstrated that blocking the signalling of a cytokine, interleukin 10, at the time of immunisation elicited significantly higher numbers of antigen specific T cells and inhibited tumour growth in mice. RESU...

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Detalles Bibliográficos
Autores principales: Pan, Xuan, Ma, Bowei, You, Xinchao, Chen, Shu, Wu, Jialing, Wang, Tianfang, Walton, Shelley F., Yuan, Jianwei, Wu, Xiaolian, Chen, Guoqiang, Wang, Yuejian, Ni, Guoying, Liu, Xiaosong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612097/
https://www.ncbi.nlm.nih.gov/pubmed/31277636
http://dx.doi.org/10.1186/s12906-019-2571-z