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Synthesized natural peptides from amphibian skin secretions increase the efficacy of a therapeutic vaccine by recruiting more T cells to the tumour site
BACKGROUND: Therapeutic vaccines against cervical cancer remain ineffective. Previously, we demonstrated that blocking the signalling of a cytokine, interleukin 10, at the time of immunisation elicited significantly higher numbers of antigen specific T cells and inhibited tumour growth in mice. RESU...
Autores principales: | Pan, Xuan, Ma, Bowei, You, Xinchao, Chen, Shu, Wu, Jialing, Wang, Tianfang, Walton, Shelley F., Yuan, Jianwei, Wu, Xiaolian, Chen, Guoqiang, Wang, Yuejian, Ni, Guoying, Liu, Xiaosong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612097/ https://www.ncbi.nlm.nih.gov/pubmed/31277636 http://dx.doi.org/10.1186/s12906-019-2571-z |
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