Napabucasin, a novel STAT3 inhibitor suppresses proliferation, invasion and stemness of glioblastoma cells

BACKGROUND: Glioblastoma (GBM) cells with stem cell-like properties are called glioma stem cells (GSCs). GSCs display highly treatment resistance and are responsible for tumor recurrence. Napabucasin (BBI608), a novel small molecule inhibitor of STAT3, has been identified to eliminate stemness-like...

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Detalles Bibliográficos
Autores principales: Han, Dongfeng, Yu, Tianfu, Dong, Nan, Wang, Bo, Sun, Fei, Jiang, Dehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612138/
https://www.ncbi.nlm.nih.gov/pubmed/31277685
http://dx.doi.org/10.1186/s13046-019-1289-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612138/
https://www.ncbi.nlm.nih.gov/pubmed/31277685
http://dx.doi.org/10.1186/s13046-019-1289-6

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