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Nanomedicine-driven neuropathic pain relief in a rat model is associated with macrophage polarity and mast cell activation

We explored the immune neuropathology underlying multi-day relief from neuropathic pain in a rat model initiated at the sciatic nerve, by using a nanoemulsion-based nanomedicine as a biological probe. The nanomedicine is theranostic: both therapeutic (containing celecoxib drug) and diagnostic (conta...

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Detalles Bibliográficos
Autores principales:	Saleem, Muzamil, Deal, Brooke, Nehl, Emily, Janjic, Jelena M., Pollock, John A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612172/ https://www.ncbi.nlm.nih.gov/pubmed/31277709 http://dx.doi.org/10.1186/s40478-019-0762-y

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