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A case of acute promyelocytic leukemia variant with derivative chromosome 3 der(3)t(3;8) associated with 8q partial gain

BACKGROUND: Acute promyelocytic leukemia (APL) is characterized by fusion of PML/RARα genes as a result of t(15;17)(q24;q21). APL is now one of the curable hematological malignancies thanks to molecularly targeted therapies based on all-trans retinoic acid (ATRA) and arsenic trioxide (ATX). Extramed...

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Detalles Bibliográficos
Autores principales:	Nozza, Filomena, Vona, Gabriella, Trino, Stefania, D’Auria, Fiorella, La Rocca, Francesco, Grieco, Vitina, Possidente, Luciana, De Luca, Luciana, Musto, Pellegrino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612227/ https://www.ncbi.nlm.nih.gov/pubmed/31312256 http://dx.doi.org/10.1186/s13039-019-0445-1

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