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Comparison of three congruent patient-specific cell types for the modelling of a human genetic Schwann-cell disorder

Patient-specific human induced pluripotent stem cells (hiPSCs) hold great promise for the modelling of genetic disorders. However, these cells display wide intra-individual and inter-individual variations in gene expression, making it challenging to distinguish true-positive and false-positive pheno...

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Detalles Bibliográficos
Autores principales: Mukherjee-Clavin, Bipasha, Mi, Ruifa, Kern, Barbara, Choi, In Young, Lim, Hotae, Oh, Yohan, Lannon, Benjamin, Kim, Kevin J., Bell, Shaughn, Hur, Junho K., Hwang, Woochang, Hyun Che, Young, Habib, Omer, Baloh, Robert H., Eggan, Kevin, Brandacher, Gerald, Hoke, Ahmet, Studer, Lorenz, Jun Kim, Yong, Lee, Gabsang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612317/
https://www.ncbi.nlm.nih.gov/pubmed/30962586
http://dx.doi.org/10.1038/s41551-019-0381-8