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A 3D Multiscale Model to Explore the Role of EGFR Overexpression in Tumourigenesis
The epidermal growth factor receptor (EGFR) signalling cascade is one of the main pathways that regulate the survival and division of mammalian cells. It is also one of the most altered transduction pathways in cancer. Acquired mutations in the EGFR/ERK pathway can cause the overexpression of EGFR o...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612322/ https://www.ncbi.nlm.nih.gov/pubmed/31016574 http://dx.doi.org/10.1007/s11538-019-00607-y |