Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum

The appearance of multi‐drug resistant strains of malaria poses a major challenge to human health and validated drug targets are urgently required. To define a protein's function in vivo and thereby validate it as a drug target, highly specific tools are required that modify protein function wi...

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Detalles Bibliográficos
Autores principales: Batista, Fernando A., Bosch, Soraya S., Butzloff, Sabine, Lunev, Sergey, Meissner, Kamila A., Linzke, Marleen, Romero, Atilio R., Wang, Chao, Müller, Ingrid B., Dömling, Alexander S. S., Groves, Matthew R., Wrenger, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612543/
https://www.ncbi.nlm.nih.gov/pubmed/30821109
http://dx.doi.org/10.1002/mbo3.779

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