Transcriptomic analysis of human IL‐7 receptor alpha( low) and( high) effector memory CD8(+) T cells reveals an age‐associated signature linked to influenza vaccine response in older adults

Here, we investigated the relationship of the age‐associated expansion of IL‐7 receptor alpha low (IL‐7Rα(low)) effector memory (EM) CD8(+) T cells with the global transcriptomic profile of peripheral blood cells in humans. We found 231 aging signature genes of IL‐7Rα(low) EM CD8(+ )T cells that cor...

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Detalles Bibliográficos
Autores principales: Park, Hong‐Jai, Shin, Min Sun, Kim, Minhyung, Bilsborrow, Joshua B., Mohanty, Subhasis, Montgomery, Ruth R., Shaw, Albert C., You, Sungyong, Kang, Insoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612637/
https://www.ncbi.nlm.nih.gov/pubmed/31044512
http://dx.doi.org/10.1111/acel.12960

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