Transcription factor networks in aged naïve CD4 T cells bias lineage differentiation

With reduced thymic activity, the population of naïve T cells in humans is maintained by homeostatic proliferation throughout adult life. In young adults, naïve CD4 T cells have enormous proliferative potential and plasticity to differentiate into different lineages. Here, we explored whether naïve...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Bin, Li, Guangjin, Ye, Zhongde, Gustafson, Claire E., Tian, Lu, Weyand, Cornelia M., Goronzy, Jörg J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640/
https://www.ncbi.nlm.nih.gov/pubmed/31264370
http://dx.doi.org/10.1111/acel.12957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640/
https://www.ncbi.nlm.nih.gov/pubmed/31264370
http://dx.doi.org/10.1111/acel.12957

Ejemplares similares