Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence

Cellular senescence is triggered by diverse stimuli and is characterized by long‐term growth arrest and secretion of cytokines and chemokines (termed the SASP—senescence‐associated secretory phenotype). Senescence can be organismally beneficial as it can prevent the propagation of damaged or mutated...

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Detalles Bibliográficos
Autores principales: Pantazi, Asimina, Quintanilla, Andrea, Hari, Priya, Tarrats, Nuria, Parasyraki, Eleftheria, Dix, Flora L., Patel, Jaiyogesh, Chandra, Tamir, Acosta, Juan Carlos, Finch, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612703/
https://www.ncbi.nlm.nih.gov/pubmed/31148378
http://dx.doi.org/10.1111/acel.12981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612703/
https://www.ncbi.nlm.nih.gov/pubmed/31148378
http://dx.doi.org/10.1111/acel.12981

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