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Estimación de la demanda de medicamentos antichagásicos: una contribución para el acceso en América Latina

OBJECTIVE. Describe a tool to estimate demand for benznidazole and nifurtimox to treat Chagas disease, and report on its implementation in a group of Latin American countries. METHODS. The project was carried out in the following stages: 1) development of a tool to estimate demand, and definition of...

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Autores principales: Costa Chaves, Gabriela, Abi-Saab Arrieche, Mariana, Rode, Joelle, Mechali, Daniel, Ouverney Reis, Priscileyne, Vieira Alves, Renato, Stobbaerts, Eric, Girón Aguilar, Nora, Ribeiro, Isabela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Organización Panamericana de la Salud 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612731/
https://www.ncbi.nlm.nih.gov/pubmed/28614468
http://dx.doi.org/10.26633/RPSP.2017.45
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author Costa Chaves, Gabriela
Abi-Saab Arrieche, Mariana
Rode, Joelle
Mechali, Daniel
Ouverney Reis, Priscileyne
Vieira Alves, Renato
Stobbaerts, Eric
Girón Aguilar, Nora
Ribeiro, Isabela
author_facet Costa Chaves, Gabriela
Abi-Saab Arrieche, Mariana
Rode, Joelle
Mechali, Daniel
Ouverney Reis, Priscileyne
Vieira Alves, Renato
Stobbaerts, Eric
Girón Aguilar, Nora
Ribeiro, Isabela
author_sort Costa Chaves, Gabriela
collection PubMed
description OBJECTIVE. Describe a tool to estimate demand for benznidazole and nifurtimox to treat Chagas disease, and report on its implementation in a group of Latin American countries. METHODS. The project was carried out in the following stages: 1) development of a tool to estimate demand, and definition of the evaluation and decision variables to estimate demand 2) data collection via a questionnaire completed by representatives of control programs, complemented with data from the literature; 3) presentation of the tool, followed by validation, and adaptation by representatives of the control programs in order to plan drug procurement for 2012 and 2013; and 4) further analysis of the obtained data, especially regarding benznidazole, and comparison of country estimates. RESULTS. Fourteen endemic countries of Latin America took part in the third stage, and a consolidated estimate was made. The number of estimated treatments, based on the number of tablets per treatment established in the regimen of reference was: 867 in the group under 1 year of age; 2 042 835 in the group from 1 to 15 years old; 2 028 in the group from 15 to 20 years old; and 10 248 in adults over 20. This means that it is possible to provide benznidazole to less than 1% of people for whom treatment is indicated. CONCLUSIONS. The development and systematic use of demand management tools can play a key role in helping to provide access to the anti-Chagas drugs. There is a significant gap between the projected demand for drugs and current estimates of prevalence rates.
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spelling pubmed-66127312019-07-30 Estimación de la demanda de medicamentos antichagásicos: una contribución para el acceso en América Latina Costa Chaves, Gabriela Abi-Saab Arrieche, Mariana Rode, Joelle Mechali, Daniel Ouverney Reis, Priscileyne Vieira Alves, Renato Stobbaerts, Eric Girón Aguilar, Nora Ribeiro, Isabela Rev Panam Salud Publica Informe Especial OBJECTIVE. Describe a tool to estimate demand for benznidazole and nifurtimox to treat Chagas disease, and report on its implementation in a group of Latin American countries. METHODS. The project was carried out in the following stages: 1) development of a tool to estimate demand, and definition of the evaluation and decision variables to estimate demand 2) data collection via a questionnaire completed by representatives of control programs, complemented with data from the literature; 3) presentation of the tool, followed by validation, and adaptation by representatives of the control programs in order to plan drug procurement for 2012 and 2013; and 4) further analysis of the obtained data, especially regarding benznidazole, and comparison of country estimates. RESULTS. Fourteen endemic countries of Latin America took part in the third stage, and a consolidated estimate was made. The number of estimated treatments, based on the number of tablets per treatment established in the regimen of reference was: 867 in the group under 1 year of age; 2 042 835 in the group from 1 to 15 years old; 2 028 in the group from 15 to 20 years old; and 10 248 in adults over 20. This means that it is possible to provide benznidazole to less than 1% of people for whom treatment is indicated. CONCLUSIONS. The development and systematic use of demand management tools can play a key role in helping to provide access to the anti-Chagas drugs. There is a significant gap between the projected demand for drugs and current estimates of prevalence rates. Organización Panamericana de la Salud 2017-04-14 /pmc/articles/PMC6612731/ /pubmed/28614468 http://dx.doi.org/10.26633/RPSP.2017.45 Text en https://creativecommons.org/licenses/by/4.0/  
spellingShingle Informe Especial
Costa Chaves, Gabriela
Abi-Saab Arrieche, Mariana
Rode, Joelle
Mechali, Daniel
Ouverney Reis, Priscileyne
Vieira Alves, Renato
Stobbaerts, Eric
Girón Aguilar, Nora
Ribeiro, Isabela
Estimación de la demanda de medicamentos antichagásicos: una contribución para el acceso en América Latina
title Estimación de la demanda de medicamentos antichagásicos: una contribución para el acceso en América Latina
title_full Estimación de la demanda de medicamentos antichagásicos: una contribución para el acceso en América Latina
title_fullStr Estimación de la demanda de medicamentos antichagásicos: una contribución para el acceso en América Latina
title_full_unstemmed Estimación de la demanda de medicamentos antichagásicos: una contribución para el acceso en América Latina
title_short Estimación de la demanda de medicamentos antichagásicos: una contribución para el acceso en América Latina
title_sort estimación de la demanda de medicamentos antichagásicos: una contribución para el acceso en américa latina
topic Informe Especial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612731/
https://www.ncbi.nlm.nih.gov/pubmed/28614468
http://dx.doi.org/10.26633/RPSP.2017.45
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