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Inheritance and variability of kinetic gene expression parameters in microbial cells: modeling and inference from lineage tree data

MOTIVATION: Modern experimental technologies enable monitoring of gene expression dynamics in individual cells and quantification of its variability in isogenic microbial populations. Among the sources of this variability is the randomness that affects inheritance of gene expression factors at cell...

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Detalles Bibliográficos
Autores principales: Marguet, Aline, Lavielle, Marc, Cinquemani, Eugenio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612834/
https://www.ncbi.nlm.nih.gov/pubmed/31510690
http://dx.doi.org/10.1093/bioinformatics/btz378