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ShaKer: RNA SHAPE prediction using graph kernel

SUMMARY: SHAPE experiments are used to probe the structure of RNA molecules. We present ShaKer to predict SHAPE data for RNA using a graph-kernel-based machine learning approach that is trained on experimental SHAPE information. While other available methods require a manually curated reference stru...

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Detalles Bibliográficos
Autores principales: Mautner, Stefan, Montaseri, Soheila, Miladi, Milad, Raden, Martin, Costa, Fabrizio, Backofen, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612843/
https://www.ncbi.nlm.nih.gov/pubmed/31510707
http://dx.doi.org/10.1093/bioinformatics/btz395