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A novel measure of non-coding genome conservation identifies genomic regulatory blocks within primates
MOTIVATION: Clusters of extremely conserved non-coding elements (CNEs) mark genomic regions devoted to cis-regulation of key developmental genes in Metazoa. We have recently shown that their span coincides with that of topologically associating domains (TADs), making them useful for estimating conse...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612856/ https://www.ncbi.nlm.nih.gov/pubmed/30535005 http://dx.doi.org/10.1093/bioinformatics/bty1014 |