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A novel measure of non-coding genome conservation identifies genomic regulatory blocks within primates

MOTIVATION: Clusters of extremely conserved non-coding elements (CNEs) mark genomic regions devoted to cis-regulation of key developmental genes in Metazoa. We have recently shown that their span coincides with that of topologically associating domains (TADs), making them useful for estimating conse...

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Detalles Bibliográficos
Autores principales:	Nash, Alexander J, Lenhard, Boris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612856/ https://www.ncbi.nlm.nih.gov/pubmed/30535005 http://dx.doi.org/10.1093/bioinformatics/bty1014

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