Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is the second leading cause of mortality among cancers. It has been found that long noncoding RNAs (lncRNAs) are involved in many human cancers, including liver cancer. It has been identified that carcinogenic and tumor-suppressing lncRNAs are associated with complex p...

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Detalles Bibliográficos
Autores principales: Shi, Haihong, Xu, Yuxin, Yi, Xin, Fang, Dandan, Hou, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612982/
https://www.ncbi.nlm.nih.gov/pubmed/31341758
http://dx.doi.org/10.1155/2019/1534607
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author Shi, Haihong
Xu, Yuxin
Yi, Xin
Fang, Dandan
Hou, Xia
author_facet Shi, Haihong
Xu, Yuxin
Yi, Xin
Fang, Dandan
Hou, Xia
author_sort Shi, Haihong
collection PubMed
description Hepatocellular carcinoma (HCC) is the second leading cause of mortality among cancers. It has been found that long noncoding RNAs (lncRNAs) are involved in many human cancers, including liver cancer. It has been identified that carcinogenic and tumor-suppressing lncRNAs are associated with complex processes in liver cancer. These lncRNAs may participate in a variety of pathological and biological activities, such as cell proliferation, apoptosis, invasion, and metastasis. Here, we review the regulation and function of lncRNA in liver cancer and evaluate the potential of lncRNA as a new goal for liver cancer.
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spelling pubmed-66129822019-07-24 Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma Shi, Haihong Xu, Yuxin Yi, Xin Fang, Dandan Hou, Xia Anal Cell Pathol (Amst) Review Article Hepatocellular carcinoma (HCC) is the second leading cause of mortality among cancers. It has been found that long noncoding RNAs (lncRNAs) are involved in many human cancers, including liver cancer. It has been identified that carcinogenic and tumor-suppressing lncRNAs are associated with complex processes in liver cancer. These lncRNAs may participate in a variety of pathological and biological activities, such as cell proliferation, apoptosis, invasion, and metastasis. Here, we review the regulation and function of lncRNA in liver cancer and evaluate the potential of lncRNA as a new goal for liver cancer. Hindawi 2019-06-24 /pmc/articles/PMC6612982/ /pubmed/31341758 http://dx.doi.org/10.1155/2019/1534607 Text en Copyright © 2019 Haihong Shi et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Shi, Haihong
Xu, Yuxin
Yi, Xin
Fang, Dandan
Hou, Xia
Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma
title Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma
title_full Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma
title_fullStr Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma
title_full_unstemmed Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma
title_short Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma
title_sort current research progress on long noncoding rnas associated with hepatocellular carcinoma
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612982/
https://www.ncbi.nlm.nih.gov/pubmed/31341758
http://dx.doi.org/10.1155/2019/1534607
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