LSD1 regulates Notch and PI3K/Akt/mTOR pathways through binding the promoter regions of Notch target genes in esophageal squamous cell carcinoma

Background: The aberrant activation of Lysine-specific demethylase 1(LSD1), Notch and PI3K/Akt/mTOR signaling pathways were frequently happened in many cancers, including esophageal squamous cell carcinoma (ESCC). However, the regulatory relationship between LSD1 and Notch as well as PI3K/Akt/mTOR p...

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Detalles Bibliográficos
Autores principales: Hou, Guiqin, Zhao, Qi, Zhang, Mengying, Wang, Peng, Ye, Hua, Wang, Yang, Ren, Yandan, Zhang, Jianying, Lu, Zhaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613024/
https://www.ncbi.nlm.nih.gov/pubmed/31308693
http://dx.doi.org/10.2147/OTT.S207238

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