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α2-Chimaerin is essential for neural stem cell homeostasis in mouse adult neurogenesis

Adult hippocampal neurogenesis involves the lifelong generation of neurons. The process depends on the homeostasis of the production of neurons and maintenance of the adult neural stem cell (NSC) pool. Here, we report that α2-chimaerin, a Rho GTPase-activating protein, is essential for NSC homeostas...

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Detalles Bibliográficos
Autores principales: Su, Yi-Ting, Lau, Shun-Fat, Ip, Jacque P. K., Cheung, Kit, Cheung, Tom H. T., Fu, Amy K. Y., Ip, Nancy Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613132/
https://www.ncbi.nlm.nih.gov/pubmed/31209021
http://dx.doi.org/10.1073/pnas.1903891116