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Leptin’s hunger-suppressing effects are mediated by the hypothalamic–pituitary–adrenocortical axis in rodents

Leptin informs the brain about sufficiency of fuel stores. When insufficient, leptin levels fall, triggering compensatory increases in appetite. Falling leptin is first sensed by hypothalamic neurons, which then initiate adaptive responses. With regard to hunger, it is thought that leptin-sensing ne...

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Detalles Bibliográficos
Autores principales: Perry, Rachel J., Resch, Jon M., Douglass, Amelia M., Madara, Joseph C., Rabin-Court, Aviva, Kucukdereli, Hakan, Wu, Chen, Song, Joongyu D., Lowell, Bradford B., Shulman, Gerald I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613139/
https://www.ncbi.nlm.nih.gov/pubmed/31213533
http://dx.doi.org/10.1073/pnas.1901795116