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Activation of the P38/CREB/MMP13 axis is associated with osteoarthritis

PURPOSES: Osteoarthritis (OA) is a common joint disease characterized by the degradation of articular cartilage and joint inflammation. Interleukin-1ß induces P38/cAMP response element binding protein (CREB) pathway activation, resulting in increased expression of matrix metallopeptidase-13 (MMP13)...

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Detalles Bibliográficos
Autores principales:	Ji, Bin, Ma, Yan, Wang, Haimin, Fang, Xiangqian, Shi, Peihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613348/ https://www.ncbi.nlm.nih.gov/pubmed/31308631 http://dx.doi.org/10.2147/DDDT.S209626

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