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Cellular frustration algorithms for anomaly detection applications

Cellular frustrated models have been developed to describe how the adaptive immune system works. They are composed by independent agents that continuously pair and unpair depending on the information that one sub-set of these agents display. The emergent dynamics is sensitive to changes in the displ...

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Detalles Bibliográficos
Autores principales: Faria, Bruno, Vistulo de Abreu, Fernao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613704/
https://www.ncbi.nlm.nih.gov/pubmed/31283758
http://dx.doi.org/10.1371/journal.pone.0218930
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author Faria, Bruno
Vistulo de Abreu, Fernao
author_facet Faria, Bruno
Vistulo de Abreu, Fernao
author_sort Faria, Bruno
collection PubMed
description Cellular frustrated models have been developed to describe how the adaptive immune system works. They are composed by independent agents that continuously pair and unpair depending on the information that one sub-set of these agents display. The emergent dynamics is sensitive to changes in the displayed information and can be used to detect anomalies, which can be important to accomplish the immune system main function of protecting the host. Therefore, it has been hypothesized that these models could be adequate to model the immune system activation. Likewise it has been hypothesized that these models could provide inspiration to develop new artificial intelligence algorithms for data mining applications. However, computational algorithms do not need to follow strictly the immunological reality. Here, we investigate efficient implementation strategies of these immune inspired ideas for anomaly detection applications and use real data to compare the performance of cellular frustration algorithms with standard implementations of one-class support vector machines and deep autoencoders. Our results demonstrate that more efficient implementations of cellular frustration algorithms are possible and also that cellular frustration algorithms can be advantageous for semi-supervised anomaly detection applications given their robustness and accuracy.
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spelling pubmed-66137042019-07-23 Cellular frustration algorithms for anomaly detection applications Faria, Bruno Vistulo de Abreu, Fernao PLoS One Research Article Cellular frustrated models have been developed to describe how the adaptive immune system works. They are composed by independent agents that continuously pair and unpair depending on the information that one sub-set of these agents display. The emergent dynamics is sensitive to changes in the displayed information and can be used to detect anomalies, which can be important to accomplish the immune system main function of protecting the host. Therefore, it has been hypothesized that these models could be adequate to model the immune system activation. Likewise it has been hypothesized that these models could provide inspiration to develop new artificial intelligence algorithms for data mining applications. However, computational algorithms do not need to follow strictly the immunological reality. Here, we investigate efficient implementation strategies of these immune inspired ideas for anomaly detection applications and use real data to compare the performance of cellular frustration algorithms with standard implementations of one-class support vector machines and deep autoencoders. Our results demonstrate that more efficient implementations of cellular frustration algorithms are possible and also that cellular frustration algorithms can be advantageous for semi-supervised anomaly detection applications given their robustness and accuracy. Public Library of Science 2019-07-08 /pmc/articles/PMC6613704/ /pubmed/31283758 http://dx.doi.org/10.1371/journal.pone.0218930 Text en © 2019 Faria, Vistulo de Abreu http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Faria, Bruno
Vistulo de Abreu, Fernao
Cellular frustration algorithms for anomaly detection applications
title Cellular frustration algorithms for anomaly detection applications
title_full Cellular frustration algorithms for anomaly detection applications
title_fullStr Cellular frustration algorithms for anomaly detection applications
title_full_unstemmed Cellular frustration algorithms for anomaly detection applications
title_short Cellular frustration algorithms for anomaly detection applications
title_sort cellular frustration algorithms for anomaly detection applications
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613704/
https://www.ncbi.nlm.nih.gov/pubmed/31283758
http://dx.doi.org/10.1371/journal.pone.0218930
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