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Neuroimaging studies on cognitive impairment due to cerebral small vessel disease
Vascular cognitive impairment (VCI) is a major contributor to age-related dementing illnesses which imposes a tremendous burden on families and society. It is a heterogeneous group of brain disorders. However, cerebral small vessel disease (CSVD) accounts for about 50%–70% of VCI, which represented...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613873/ https://www.ncbi.nlm.nih.gov/pubmed/31338220 http://dx.doi.org/10.1136/svn-2018-000209 |
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author | Du, Jing Xu, Qun |
author_facet | Du, Jing Xu, Qun |
author_sort | Du, Jing |
collection | PubMed |
description | Vascular cognitive impairment (VCI) is a major contributor to age-related dementing illnesses which imposes a tremendous burden on families and society. It is a heterogeneous group of brain disorders. However, cerebral small vessel disease (CSVD) accounts for about 50%–70% of VCI, which represented a more homogeneous subtype of VCI. Advanced multimodal neuroimaging techniques like brain network connectome analyses are currently applied to explore the underlying mechanism of VCI. Some progress in the field of structural and functional brain network researches on a poststroke longitudinal CSVD cohort (Renji CSVD Cohort Study) was reported. Global and regional brain network characters were compared between patients with CSVD and healthy control. It suggested that distributed brain structural network disruption may play a pivot role in the cognitive decline. The results showed that brain structural network characters have distinctive differentiating capacity on the cognition of patients with CSVD. |
format | Online Article Text |
id | pubmed-6613873 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-66138732019-07-23 Neuroimaging studies on cognitive impairment due to cerebral small vessel disease Du, Jing Xu, Qun Stroke Vasc Neurol Review Vascular cognitive impairment (VCI) is a major contributor to age-related dementing illnesses which imposes a tremendous burden on families and society. It is a heterogeneous group of brain disorders. However, cerebral small vessel disease (CSVD) accounts for about 50%–70% of VCI, which represented a more homogeneous subtype of VCI. Advanced multimodal neuroimaging techniques like brain network connectome analyses are currently applied to explore the underlying mechanism of VCI. Some progress in the field of structural and functional brain network researches on a poststroke longitudinal CSVD cohort (Renji CSVD Cohort Study) was reported. Global and regional brain network characters were compared between patients with CSVD and healthy control. It suggested that distributed brain structural network disruption may play a pivot role in the cognitive decline. The results showed that brain structural network characters have distinctive differentiating capacity on the cognition of patients with CSVD. BMJ Publishing Group 2019-04-05 /pmc/articles/PMC6613873/ /pubmed/31338220 http://dx.doi.org/10.1136/svn-2018-000209 Text en © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Review Du, Jing Xu, Qun Neuroimaging studies on cognitive impairment due to cerebral small vessel disease |
title | Neuroimaging studies on cognitive impairment due to cerebral small vessel disease |
title_full | Neuroimaging studies on cognitive impairment due to cerebral small vessel disease |
title_fullStr | Neuroimaging studies on cognitive impairment due to cerebral small vessel disease |
title_full_unstemmed | Neuroimaging studies on cognitive impairment due to cerebral small vessel disease |
title_short | Neuroimaging studies on cognitive impairment due to cerebral small vessel disease |
title_sort | neuroimaging studies on cognitive impairment due to cerebral small vessel disease |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613873/ https://www.ncbi.nlm.nih.gov/pubmed/31338220 http://dx.doi.org/10.1136/svn-2018-000209 |
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