METTL3 and ALKBH5 oppositely regulate m(6)A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes

N(6)-methyladenosine (m(6)A) mRNA modifications play critical roles in various biological processes. However, no study addresses the role of m(6)A in macroautophagy/autophagy. Here, we show that m(6)A modifications are increased in H/R-treated cardiomyocytes and ischemia/reperfusion (I/R)-treated mi...

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Detalles Bibliográficos
Autores principales: Song, Huiwen, Feng, Xing, Zhang, Heng, Luo, Yunmei, Huang, Juan, Lin, Meihua, Jin, Junfei, Ding, Xue, Wu, Shujing, Huang, He, Yu, Tian, Zhang, Mukun, Hong, Haiou, Yao, Shihua, Zhao, Yongxiang, Zhang, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613905/
https://www.ncbi.nlm.nih.gov/pubmed/30870073
http://dx.doi.org/10.1080/15548627.2019.1586246

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