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Multisite phosphorylation code of CDK

The quantitative model of cyclin-dependent kinase (CDK) function states that cyclins temporally order cell cycle events at different CDK activity levels, or thresholds. The model lacks a mechanistic explanation, as it is not understood how different thresholds are encoded into substrates. We show th...

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Detalles Bibliográficos
Autores principales:	Örd, Mihkel, Möll, Kaidi, Agerova, Alissa, Kivi, Rait, Faustova, Ilona, Venta, Rainis, Valk, Ervin, Loog, Mart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614033/ https://www.ncbi.nlm.nih.gov/pubmed/31270471 http://dx.doi.org/10.1038/s41594-019-0256-4

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