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Analgesic Effect of Toll-like Receptor 4 Antagonistic Peptide 2 on Mechanical Allodynia Induced with Spinal Nerve Ligation in Rats

Neuroinflammation is one of the key mechanisms of neuropathic pain, which is primarily mediated by the Toll-like receptor 4 (TLR4) signaling pathways in microglia. Therefore, TLR4 may be a reasonable target for treatment of neuropathic pain. Here, we examined the analgesic effect of TLR4 antagonisti...

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Detalles Bibliográficos
Autores principales: Yin, Yuhua, Park, Hyewon, Lee, Sun Yeul, Lee, Won-hyung, Song, Hee-Jung, Kim, Jinhyun, Kim, Dong Woon, Hong, Jinpyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614064/
https://www.ncbi.nlm.nih.gov/pubmed/31308795
http://dx.doi.org/10.5607/en.2019.28.3.352