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Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes

This data article provides atomic force microscopy (AFM) amplitude images of botulinum toxin complex (TC) molecules produced by Clostridium botulinum serotype D strain. C. botulinum produces different-sized TC molecules, such as a complex of botulinum neurotoxin and nontoxic nonhemagglutinin protein...

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Autores principales: Miyashita, Shin-Ichiro, Sagane, Yoshimasa, Uchino, Takamasa, Karatsu, Shura, Hosoya, Keita, Huang, Ihsun, Niwa, Koichi, Watanabe, Toshihiro, Niimura, Yoichi, Suzuki, Tomonori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614086/
https://www.ncbi.nlm.nih.gov/pubmed/31321275
http://dx.doi.org/10.1016/j.dib.2019.104193
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author Miyashita, Shin-Ichiro
Sagane, Yoshimasa
Uchino, Takamasa
Karatsu, Shura
Hosoya, Keita
Huang, Ihsun
Niwa, Koichi
Watanabe, Toshihiro
Niimura, Yoichi
Suzuki, Tomonori
author_facet Miyashita, Shin-Ichiro
Sagane, Yoshimasa
Uchino, Takamasa
Karatsu, Shura
Hosoya, Keita
Huang, Ihsun
Niwa, Koichi
Watanabe, Toshihiro
Niimura, Yoichi
Suzuki, Tomonori
author_sort Miyashita, Shin-Ichiro
collection PubMed
description This data article provides atomic force microscopy (AFM) amplitude images of botulinum toxin complex (TC) molecules produced by Clostridium botulinum serotype D strain. C. botulinum produces different-sized TC molecules, such as a complex of botulinum neurotoxin and nontoxic nonhemagglutinin proteins (M-TC) and complex of M-TC and hemagglutinin subcomplex (L-TC). In this data article, the M and L-TC produced by serotype D strain 4947 were imaged by AFM. The M-TC molecule had a globular structure with a 30.5-nm diameter and a 2.1-nm height, while the L-TC molecule had a distinct structure in which several spheres were connected to a globular structure that was 40.7 nm in diameter and 3.5 nm in height.
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spelling pubmed-66140862019-07-18 Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes Miyashita, Shin-Ichiro Sagane, Yoshimasa Uchino, Takamasa Karatsu, Shura Hosoya, Keita Huang, Ihsun Niwa, Koichi Watanabe, Toshihiro Niimura, Yoichi Suzuki, Tomonori Data Brief Biochemistry, Genetics and Molecular Biology This data article provides atomic force microscopy (AFM) amplitude images of botulinum toxin complex (TC) molecules produced by Clostridium botulinum serotype D strain. C. botulinum produces different-sized TC molecules, such as a complex of botulinum neurotoxin and nontoxic nonhemagglutinin proteins (M-TC) and complex of M-TC and hemagglutinin subcomplex (L-TC). In this data article, the M and L-TC produced by serotype D strain 4947 were imaged by AFM. The M-TC molecule had a globular structure with a 30.5-nm diameter and a 2.1-nm height, while the L-TC molecule had a distinct structure in which several spheres were connected to a globular structure that was 40.7 nm in diameter and 3.5 nm in height. Elsevier 2019-06-25 /pmc/articles/PMC6614086/ /pubmed/31321275 http://dx.doi.org/10.1016/j.dib.2019.104193 Text en © 2019 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Biochemistry, Genetics and Molecular Biology
Miyashita, Shin-Ichiro
Sagane, Yoshimasa
Uchino, Takamasa
Karatsu, Shura
Hosoya, Keita
Huang, Ihsun
Niwa, Koichi
Watanabe, Toshihiro
Niimura, Yoichi
Suzuki, Tomonori
Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes
title Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes
title_full Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes
title_fullStr Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes
title_full_unstemmed Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes
title_short Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes
title_sort atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes
topic Biochemistry, Genetics and Molecular Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614086/
https://www.ncbi.nlm.nih.gov/pubmed/31321275
http://dx.doi.org/10.1016/j.dib.2019.104193
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