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Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes
This data article provides atomic force microscopy (AFM) amplitude images of botulinum toxin complex (TC) molecules produced by Clostridium botulinum serotype D strain. C. botulinum produces different-sized TC molecules, such as a complex of botulinum neurotoxin and nontoxic nonhemagglutinin protein...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614086/ https://www.ncbi.nlm.nih.gov/pubmed/31321275 http://dx.doi.org/10.1016/j.dib.2019.104193 |
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author | Miyashita, Shin-Ichiro Sagane, Yoshimasa Uchino, Takamasa Karatsu, Shura Hosoya, Keita Huang, Ihsun Niwa, Koichi Watanabe, Toshihiro Niimura, Yoichi Suzuki, Tomonori |
author_facet | Miyashita, Shin-Ichiro Sagane, Yoshimasa Uchino, Takamasa Karatsu, Shura Hosoya, Keita Huang, Ihsun Niwa, Koichi Watanabe, Toshihiro Niimura, Yoichi Suzuki, Tomonori |
author_sort | Miyashita, Shin-Ichiro |
collection | PubMed |
description | This data article provides atomic force microscopy (AFM) amplitude images of botulinum toxin complex (TC) molecules produced by Clostridium botulinum serotype D strain. C. botulinum produces different-sized TC molecules, such as a complex of botulinum neurotoxin and nontoxic nonhemagglutinin proteins (M-TC) and complex of M-TC and hemagglutinin subcomplex (L-TC). In this data article, the M and L-TC produced by serotype D strain 4947 were imaged by AFM. The M-TC molecule had a globular structure with a 30.5-nm diameter and a 2.1-nm height, while the L-TC molecule had a distinct structure in which several spheres were connected to a globular structure that was 40.7 nm in diameter and 3.5 nm in height. |
format | Online Article Text |
id | pubmed-6614086 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-66140862019-07-18 Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes Miyashita, Shin-Ichiro Sagane, Yoshimasa Uchino, Takamasa Karatsu, Shura Hosoya, Keita Huang, Ihsun Niwa, Koichi Watanabe, Toshihiro Niimura, Yoichi Suzuki, Tomonori Data Brief Biochemistry, Genetics and Molecular Biology This data article provides atomic force microscopy (AFM) amplitude images of botulinum toxin complex (TC) molecules produced by Clostridium botulinum serotype D strain. C. botulinum produces different-sized TC molecules, such as a complex of botulinum neurotoxin and nontoxic nonhemagglutinin proteins (M-TC) and complex of M-TC and hemagglutinin subcomplex (L-TC). In this data article, the M and L-TC produced by serotype D strain 4947 were imaged by AFM. The M-TC molecule had a globular structure with a 30.5-nm diameter and a 2.1-nm height, while the L-TC molecule had a distinct structure in which several spheres were connected to a globular structure that was 40.7 nm in diameter and 3.5 nm in height. Elsevier 2019-06-25 /pmc/articles/PMC6614086/ /pubmed/31321275 http://dx.doi.org/10.1016/j.dib.2019.104193 Text en © 2019 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Biochemistry, Genetics and Molecular Biology Miyashita, Shin-Ichiro Sagane, Yoshimasa Uchino, Takamasa Karatsu, Shura Hosoya, Keita Huang, Ihsun Niwa, Koichi Watanabe, Toshihiro Niimura, Yoichi Suzuki, Tomonori Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes |
title | Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes |
title_full | Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes |
title_fullStr | Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes |
title_full_unstemmed | Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes |
title_short | Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes |
title_sort | atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes |
topic | Biochemistry, Genetics and Molecular Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614086/ https://www.ncbi.nlm.nih.gov/pubmed/31321275 http://dx.doi.org/10.1016/j.dib.2019.104193 |
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