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Phylogenetic insight of Nonribosomal peptide synthetases (NRPS) Adenylate domain in Antibacterial potential Streptomyces BDUSMP 02 isolated from Pitchavaram Mangrove
Identification of gene clusters in Streptomyces holds promise for the discovery of regulatory pathways linked to bioactive metabolites. We isolated a broad-spectrum antibacterial potential Streptomyces sp BDUSMP 02 from mangrove sediment. We further found a distinct of phylogeny pattern for NRPS A-d...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614122/ https://www.ncbi.nlm.nih.gov/pubmed/31312078 http://dx.doi.org/10.6026/97320630015412 |
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author | Sivalingam, Periyasamy Muthuselvam, Manickam Pote, John Prabakar, Kandasamy |
author_facet | Sivalingam, Periyasamy Muthuselvam, Manickam Pote, John Prabakar, Kandasamy |
author_sort | Sivalingam, Periyasamy |
collection | PubMed |
description | Identification of gene clusters in Streptomyces holds promise for the discovery of regulatory pathways linked to bioactive metabolites. We isolated a broad-spectrum antibacterial potential Streptomyces sp BDUSMP 02 from mangrove sediment. We further found a distinct of phylogeny pattern for NRPS A-domain in the Streptomyces sp BDUSMP 02. The result suggests that Streptomyces sp BDUSMP 02 has the potential to produce a new type of antibacterial compounds belonging to NRPS type. |
format | Online Article Text |
id | pubmed-6614122 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Biomedical Informatics |
record_format | MEDLINE/PubMed |
spelling | pubmed-66141222019-07-16 Phylogenetic insight of Nonribosomal peptide synthetases (NRPS) Adenylate domain in Antibacterial potential Streptomyces BDUSMP 02 isolated from Pitchavaram Mangrove Sivalingam, Periyasamy Muthuselvam, Manickam Pote, John Prabakar, Kandasamy Bioinformation Research Article Identification of gene clusters in Streptomyces holds promise for the discovery of regulatory pathways linked to bioactive metabolites. We isolated a broad-spectrum antibacterial potential Streptomyces sp BDUSMP 02 from mangrove sediment. We further found a distinct of phylogeny pattern for NRPS A-domain in the Streptomyces sp BDUSMP 02. The result suggests that Streptomyces sp BDUSMP 02 has the potential to produce a new type of antibacterial compounds belonging to NRPS type. Biomedical Informatics 2019-06-15 /pmc/articles/PMC6614122/ /pubmed/31312078 http://dx.doi.org/10.6026/97320630015412 Text en © 2019 Biomedical Informatics http://creativecommons.org/licenses/by/3.0/ This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License. |
spellingShingle | Research Article Sivalingam, Periyasamy Muthuselvam, Manickam Pote, John Prabakar, Kandasamy Phylogenetic insight of Nonribosomal peptide synthetases (NRPS) Adenylate domain in Antibacterial potential Streptomyces BDUSMP 02 isolated from Pitchavaram Mangrove |
title | Phylogenetic insight of Nonribosomal peptide synthetases (NRPS) Adenylate domain in Antibacterial potential Streptomyces BDUSMP 02 isolated from Pitchavaram Mangrove |
title_full | Phylogenetic insight of Nonribosomal peptide synthetases (NRPS) Adenylate domain in Antibacterial potential Streptomyces BDUSMP 02 isolated from Pitchavaram Mangrove |
title_fullStr | Phylogenetic insight of Nonribosomal peptide synthetases (NRPS) Adenylate domain in Antibacterial potential Streptomyces BDUSMP 02 isolated from Pitchavaram Mangrove |
title_full_unstemmed | Phylogenetic insight of Nonribosomal peptide synthetases (NRPS) Adenylate domain in Antibacterial potential Streptomyces BDUSMP 02 isolated from Pitchavaram Mangrove |
title_short | Phylogenetic insight of Nonribosomal peptide synthetases (NRPS) Adenylate domain in Antibacterial potential Streptomyces BDUSMP 02 isolated from Pitchavaram Mangrove |
title_sort | phylogenetic insight of nonribosomal peptide synthetases (nrps) adenylate domain in antibacterial potential streptomyces bdusmp 02 isolated from pitchavaram mangrove |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614122/ https://www.ncbi.nlm.nih.gov/pubmed/31312078 http://dx.doi.org/10.6026/97320630015412 |
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