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Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora

Medicinal plants are boundless source of raw materials for the pharmaceutical. Identification of natural compounds from medicinal plant is helpful in the discovery of novel therapeutic agents. Tylophora pauciflora is a medicinal plant, which possess many biological activities such as antioxidant act...

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Autores principales: Starlin, Thangarajan, Prabha, Poochi Saravana, Thayakumar, Basanth Kumar Allen, Gopalakrishnan, Velliyur Kanniappan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614127/
https://www.ncbi.nlm.nih.gov/pubmed/31312080
http://dx.doi.org/10.6026/97320630015425
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author Starlin, Thangarajan
Prabha, Poochi Saravana
Thayakumar, Basanth Kumar Allen
Gopalakrishnan, Velliyur Kanniappan
author_facet Starlin, Thangarajan
Prabha, Poochi Saravana
Thayakumar, Basanth Kumar Allen
Gopalakrishnan, Velliyur Kanniappan
author_sort Starlin, Thangarajan
collection PubMed
description Medicinal plants are boundless source of raw materials for the pharmaceutical. Identification of natural compounds from medicinal plant is helpful in the discovery of novel therapeutic agents. Tylophora pauciflora is a medicinal plant, which possess many biological activities such as antioxidant activity, anti-inflammatory activity and anti cancer activity. There is no GC-MS analysis reported on this plant. Thus, the present study is aimed to identify the present of phyto-chemical compounds from ethanolic extract of Tylophora pauciflora using GC-MS analysis. Results, the extract possess totally 14 bioactive compounds among that natural compound of n-hexadecanoic acid has highest % peak area and it have the variety of biological activities such as; anti-oxidant, 5-alpha-reductase-inhibitor, anti-fibrinolytic, hemolytic, antimicrobial activity, hypo-cholesterolemic, nematicide, pesticide, anti-androgenic flavor and hemolytic. It is concluded that the ethanolic extract of Tylophora pauciflora have biologically active compounds. In future by isolating and identifying, these compounds can be considered to treat the human disorders.
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spelling pubmed-66141272019-07-16 Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora Starlin, Thangarajan Prabha, Poochi Saravana Thayakumar, Basanth Kumar Allen Gopalakrishnan, Velliyur Kanniappan Bioinformation Research Article Medicinal plants are boundless source of raw materials for the pharmaceutical. Identification of natural compounds from medicinal plant is helpful in the discovery of novel therapeutic agents. Tylophora pauciflora is a medicinal plant, which possess many biological activities such as antioxidant activity, anti-inflammatory activity and anti cancer activity. There is no GC-MS analysis reported on this plant. Thus, the present study is aimed to identify the present of phyto-chemical compounds from ethanolic extract of Tylophora pauciflora using GC-MS analysis. Results, the extract possess totally 14 bioactive compounds among that natural compound of n-hexadecanoic acid has highest % peak area and it have the variety of biological activities such as; anti-oxidant, 5-alpha-reductase-inhibitor, anti-fibrinolytic, hemolytic, antimicrobial activity, hypo-cholesterolemic, nematicide, pesticide, anti-androgenic flavor and hemolytic. It is concluded that the ethanolic extract of Tylophora pauciflora have biologically active compounds. In future by isolating and identifying, these compounds can be considered to treat the human disorders. Biomedical Informatics 2019-06-15 /pmc/articles/PMC6614127/ /pubmed/31312080 http://dx.doi.org/10.6026/97320630015425 Text en © 2019 Biomedical Informatics http://creativecommons.org/licenses/by/3.0/ This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Starlin, Thangarajan
Prabha, Poochi Saravana
Thayakumar, Basanth Kumar Allen
Gopalakrishnan, Velliyur Kanniappan
Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora
title Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora
title_full Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora
title_fullStr Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora
title_full_unstemmed Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora
title_short Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora
title_sort screening and gc-ms profiling of ethanolic extract of tylophora pauciflora
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614127/
https://www.ncbi.nlm.nih.gov/pubmed/31312080
http://dx.doi.org/10.6026/97320630015425
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