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Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora
Medicinal plants are boundless source of raw materials for the pharmaceutical. Identification of natural compounds from medicinal plant is helpful in the discovery of novel therapeutic agents. Tylophora pauciflora is a medicinal plant, which possess many biological activities such as antioxidant act...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614127/ https://www.ncbi.nlm.nih.gov/pubmed/31312080 http://dx.doi.org/10.6026/97320630015425 |
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author | Starlin, Thangarajan Prabha, Poochi Saravana Thayakumar, Basanth Kumar Allen Gopalakrishnan, Velliyur Kanniappan |
author_facet | Starlin, Thangarajan Prabha, Poochi Saravana Thayakumar, Basanth Kumar Allen Gopalakrishnan, Velliyur Kanniappan |
author_sort | Starlin, Thangarajan |
collection | PubMed |
description | Medicinal plants are boundless source of raw materials for the pharmaceutical. Identification of natural compounds from medicinal plant is helpful in the discovery of novel therapeutic agents. Tylophora pauciflora is a medicinal plant, which possess many biological activities such as antioxidant activity, anti-inflammatory activity and anti cancer activity. There is no GC-MS analysis reported on this plant. Thus, the present study is aimed to identify the present of phyto-chemical compounds from ethanolic extract of Tylophora pauciflora using GC-MS analysis. Results, the extract possess totally 14 bioactive compounds among that natural compound of n-hexadecanoic acid has highest % peak area and it have the variety of biological activities such as; anti-oxidant, 5-alpha-reductase-inhibitor, anti-fibrinolytic, hemolytic, antimicrobial activity, hypo-cholesterolemic, nematicide, pesticide, anti-androgenic flavor and hemolytic. It is concluded that the ethanolic extract of Tylophora pauciflora have biologically active compounds. In future by isolating and identifying, these compounds can be considered to treat the human disorders. |
format | Online Article Text |
id | pubmed-6614127 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Biomedical Informatics |
record_format | MEDLINE/PubMed |
spelling | pubmed-66141272019-07-16 Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora Starlin, Thangarajan Prabha, Poochi Saravana Thayakumar, Basanth Kumar Allen Gopalakrishnan, Velliyur Kanniappan Bioinformation Research Article Medicinal plants are boundless source of raw materials for the pharmaceutical. Identification of natural compounds from medicinal plant is helpful in the discovery of novel therapeutic agents. Tylophora pauciflora is a medicinal plant, which possess many biological activities such as antioxidant activity, anti-inflammatory activity and anti cancer activity. There is no GC-MS analysis reported on this plant. Thus, the present study is aimed to identify the present of phyto-chemical compounds from ethanolic extract of Tylophora pauciflora using GC-MS analysis. Results, the extract possess totally 14 bioactive compounds among that natural compound of n-hexadecanoic acid has highest % peak area and it have the variety of biological activities such as; anti-oxidant, 5-alpha-reductase-inhibitor, anti-fibrinolytic, hemolytic, antimicrobial activity, hypo-cholesterolemic, nematicide, pesticide, anti-androgenic flavor and hemolytic. It is concluded that the ethanolic extract of Tylophora pauciflora have biologically active compounds. In future by isolating and identifying, these compounds can be considered to treat the human disorders. Biomedical Informatics 2019-06-15 /pmc/articles/PMC6614127/ /pubmed/31312080 http://dx.doi.org/10.6026/97320630015425 Text en © 2019 Biomedical Informatics http://creativecommons.org/licenses/by/3.0/ This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License. |
spellingShingle | Research Article Starlin, Thangarajan Prabha, Poochi Saravana Thayakumar, Basanth Kumar Allen Gopalakrishnan, Velliyur Kanniappan Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora |
title | Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora |
title_full | Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora |
title_fullStr | Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora |
title_full_unstemmed | Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora |
title_short | Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora |
title_sort | screening and gc-ms profiling of ethanolic extract of tylophora pauciflora |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614127/ https://www.ncbi.nlm.nih.gov/pubmed/31312080 http://dx.doi.org/10.6026/97320630015425 |
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