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The Role of Ceramide and Sphingosine-1-Phosphate in Alzheimer’s Disease and Other Neurodegenerative Disorders

Bioactive sphingolipids—ceramide, sphingosine, and their respective 1-phosphates (C1P and S1P)—are signaling molecules serving as intracellular second messengers. Moreover, S1P acts through G protein-coupled receptors in the plasma membrane. Accumulating evidence points to sphingolipids' engage...

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Detalles Bibliográficos
Autores principales:	Czubowicz, Kinga, Jęśko, Henryk, Wencel, Przemysław, Lukiw, Walter J., Strosznajder, Robert P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614129/ https://www.ncbi.nlm.nih.gov/pubmed/30612333 http://dx.doi.org/10.1007/s12035-018-1448-3

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