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Amyloid Precursor Protein Mediates Neuronal Protection from Rotenone Toxicity

Mitochondrial complex I dysfunction is the most common respiratory chain defect in human disorders and a hotspot for neurodegenerative diseases. Amyloid precursor protein (APP) and its non-amyloidogenic processing products, in particular soluble APP α (sAPPα), have been shown to provide neuroprotect...

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Detalles Bibliográficos
Autores principales:	Cimdins, Kathryn, Waugh, Hayley S., Chrysostomou, Vicki, Lopez Sanchez, M. Isabel G., Johannsen, Vanessa A., Cook, Mark J., Crowston, Jonathan G., Hill, Andrew F., Duce, James A., Bush, Ashley I., Trounce, Ian A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614131/ https://www.ncbi.nlm.nih.gov/pubmed/30612335 http://dx.doi.org/10.1007/s12035-018-1460-7

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