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IDH Mutation Analysis in Glioma Patients by CADMA Compared with SNaPshot Assay and two Immunohistochemical Methods

Mutations in IDH1/2 genes are a marker of good prognosis for glioma patients, associated with low grade gliomas and secondary glioblastomas. Immunohistochemistry and Sanger sequencing are current standards for IDH1/2 genotyping while many other methods exist. The aim of this study was to validate Co...

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Detalles Bibliográficos
Autores principales: Urbanovska, Irena, Megova, Magdalena Houdova, Dwight, Zachary, Kalita, Ondrej, Uvirova, Magdalena, Simova, Jarmila, Tuckova, Lucie, Buzrla, Petr, Palecek, Tomas, Hajduch, Marian, Dvorackova, Jana, Drabek, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614140/
https://www.ncbi.nlm.nih.gov/pubmed/29556922
http://dx.doi.org/10.1007/s12253-018-0413-9