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The usefulness of Veno-Arterial Extracorporeal Membranous Oxygenation in Patients with Cardiogenic Shock

BACKGROUND: Venoarterial extracorporeal membranous oxygenation is a form of temporary mechanical circulatory support that gets as a salvage technique in patients with cardiogenic shock, we intended to evaluate the effect of (VA ECMO) support on hemodynamics and lactate levels in patients with cardio...

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Autores principales: Abouelwafa, Mohamed, Radwan, Waheed, Abdelfattah, Alia, Abdelbary, Akram, Khaled, Mohamed, Samy, Wael, Yousry, Mohamed, Saeed, Ahmed, Saad, Mahmood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614275/
https://www.ncbi.nlm.nih.gov/pubmed/31316656
http://dx.doi.org/10.3889/oamjms.2019.547
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author Abouelwafa, Mohamed
Radwan, Waheed
Abdelfattah, Alia
Abdelbary, Akram
Khaled, Mohamed
Samy, Wael
Yousry, Mohamed
Saeed, Ahmed
Saad, Mahmood
author_facet Abouelwafa, Mohamed
Radwan, Waheed
Abdelfattah, Alia
Abdelbary, Akram
Khaled, Mohamed
Samy, Wael
Yousry, Mohamed
Saeed, Ahmed
Saad, Mahmood
author_sort Abouelwafa, Mohamed
collection PubMed
description BACKGROUND: Venoarterial extracorporeal membranous oxygenation is a form of temporary mechanical circulatory support that gets as a salvage technique in patients with cardiogenic shock, we intended to evaluate the effect of (VA ECMO) support on hemodynamics and lactate levels in patients with cardiogenic shock. AIM: The aim of our study is to detect the ability to introduce veno-arterial extracorporeal membranous oxygenation (VA ECMO) as a temporary extracorporeal life support system (ECLS) in our unit, demonstrate the role of ECMO in cardiogenic shock patients regarding improving hemodynamics and microcirculation, and demonstrate the complications and drawbacks in our first center experience regarding VA ECMO. MATERIAL AND METHODS: This was a single-centre observational study that included 10 patients admitted with cardiogenic shock for which VA ECMO was used as mechanical circulatory support. RESULTS: The MAP increased after initiation of the support. It was 41.8 ± 9.3 mmHg and 59.5 ± 6.8 mmHg (P = 0.005). The use of VA ECMO support was associated with a statistically significant decrease in the base deficit (-10.6 ± 4.2 and -6.3 ± 7.4, P = 0.038). The serum lactate declined from 5.9 ± 3.5 mmoL/L to 0.6 ± 4.4 mmoL/L by the use of VA ECMO; a statistically significant change (P = 0.005). CONCLUSIONS: We concluded that VA ECMO as mechanical support for patients with cardiogenic shock might improve mean arterial blood pressure, base deficit and lactate clearance.
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spelling pubmed-66142752019-07-17 The usefulness of Veno-Arterial Extracorporeal Membranous Oxygenation in Patients with Cardiogenic Shock Abouelwafa, Mohamed Radwan, Waheed Abdelfattah, Alia Abdelbary, Akram Khaled, Mohamed Samy, Wael Yousry, Mohamed Saeed, Ahmed Saad, Mahmood Open Access Maced J Med Sci Clinical Science BACKGROUND: Venoarterial extracorporeal membranous oxygenation is a form of temporary mechanical circulatory support that gets as a salvage technique in patients with cardiogenic shock, we intended to evaluate the effect of (VA ECMO) support on hemodynamics and lactate levels in patients with cardiogenic shock. AIM: The aim of our study is to detect the ability to introduce veno-arterial extracorporeal membranous oxygenation (VA ECMO) as a temporary extracorporeal life support system (ECLS) in our unit, demonstrate the role of ECMO in cardiogenic shock patients regarding improving hemodynamics and microcirculation, and demonstrate the complications and drawbacks in our first center experience regarding VA ECMO. MATERIAL AND METHODS: This was a single-centre observational study that included 10 patients admitted with cardiogenic shock for which VA ECMO was used as mechanical circulatory support. RESULTS: The MAP increased after initiation of the support. It was 41.8 ± 9.3 mmHg and 59.5 ± 6.8 mmHg (P = 0.005). The use of VA ECMO support was associated with a statistically significant decrease in the base deficit (-10.6 ± 4.2 and -6.3 ± 7.4, P = 0.038). The serum lactate declined from 5.9 ± 3.5 mmoL/L to 0.6 ± 4.4 mmoL/L by the use of VA ECMO; a statistically significant change (P = 0.005). CONCLUSIONS: We concluded that VA ECMO as mechanical support for patients with cardiogenic shock might improve mean arterial blood pressure, base deficit and lactate clearance. Republic of Macedonia 2019-06-15 /pmc/articles/PMC6614275/ /pubmed/31316656 http://dx.doi.org/10.3889/oamjms.2019.547 Text en Copyright: © 2019 Mohamed Abouelwafa, Waheed Radwan, Alia Abdelfattah, Akram Abdelbary, Mohamed Khaled, Wael Samy, Mohamed Yousry, Ahmed Saeed, Mahmood Saad. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).
spellingShingle Clinical Science
Abouelwafa, Mohamed
Radwan, Waheed
Abdelfattah, Alia
Abdelbary, Akram
Khaled, Mohamed
Samy, Wael
Yousry, Mohamed
Saeed, Ahmed
Saad, Mahmood
The usefulness of Veno-Arterial Extracorporeal Membranous Oxygenation in Patients with Cardiogenic Shock
title The usefulness of Veno-Arterial Extracorporeal Membranous Oxygenation in Patients with Cardiogenic Shock
title_full The usefulness of Veno-Arterial Extracorporeal Membranous Oxygenation in Patients with Cardiogenic Shock
title_fullStr The usefulness of Veno-Arterial Extracorporeal Membranous Oxygenation in Patients with Cardiogenic Shock
title_full_unstemmed The usefulness of Veno-Arterial Extracorporeal Membranous Oxygenation in Patients with Cardiogenic Shock
title_short The usefulness of Veno-Arterial Extracorporeal Membranous Oxygenation in Patients with Cardiogenic Shock
title_sort usefulness of veno-arterial extracorporeal membranous oxygenation in patients with cardiogenic shock
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614275/
https://www.ncbi.nlm.nih.gov/pubmed/31316656
http://dx.doi.org/10.3889/oamjms.2019.547
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