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Genetic deletion of calcium/calmodulin-dependent protein kinase type II delta does not mitigate adverse myocardial remodeling in volume-overloaded hearts
Calcium/calmodulin-dependent protein kinase type II delta (CaMKIIδ), the predominant CaMKII isoform expressed in the heart, has been implicated in the progression of myocardial infarction- and pressure overload-induced pathological remodeling. However, the role of CaMKIIδ in volume overload (VO) has...
Autores principales: | Mohamed, Belal A., Elkenani, Manar, Jakubiczka-Smorag, Joanna, Buchholz, Eric, Koszewa, Sabrina, Lbik, Dawid, Schnelle, Moritz, Hasenfuss, Gerd, Toischer, Karl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614357/ https://www.ncbi.nlm.nih.gov/pubmed/31285482 http://dx.doi.org/10.1038/s41598-019-46332-3 |
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